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Pablo Aviles Selected Research

PM 01183

5/2021Evaluation of the Preclinical Efficacy of Lurbinectedin in Malignant Pleural Mesothelioma.
10/2016Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells.
5/2016Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM01183 (lurbinectedin), a novel antineoplastic agent, in mouse, rat, dog, Cynomolgus monkey and mini-pig plasma.

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Pablo Aviles Research Topics

Disease

7Neoplasms (Cancer)
01/2018 - 08/2003
2Small Cell Lung Carcinoma (Small Cell Lung Cancer)
05/2021 - 10/2016
2Ovarian Neoplasms (Ovarian Cancer)
05/2016 - 01/2015
1COVID-19
01/2022
1Disease Progression
05/2021
1Malignant Mesothelioma
05/2021
1Necrosis
01/2018
1Sarcoma (Soft Tissue Sarcoma)
01/2015
1Mesothelioma
01/2015
1Hypersensitivity (Allergy)
04/2014
1Kidney Neoplasms (Kidney Cancer)
04/2014
1Multiple Myeloma
04/2014

Drug/Important Bio-Agent (IBA)

3plitidepsin (aplidine)IBA
01/2022 - 07/2008
3Pharmaceutical PreparationsIBA
05/2021 - 04/2014
3PM 01183IBA
05/2021 - 05/2016
2PlatinumIBA
05/2021 - 05/2016
2DepsipeptidesIBA
07/2008 - 08/2003
1plocabulinIBA
01/2018
1RNA Polymerase II (RNA Polymerase B)IBA
10/2016
1DNA (Deoxyribonucleic Acid)IBA
10/2016
1Proteasome Endopeptidase Complex (Proteasome)IBA
10/2016
1UbiquitinIBA
10/2016
1Proteins (Proteins, Gene)FDA Link
10/2016
1Antineoplastic Agents (Antineoplastics)IBA
01/2015
1TrabectedinIBA
01/2015
1Bortezomib (Velcade)FDA Link
07/2008
1Alkylating AgentsIBA
07/2008
1AnthracyclinesIBA
07/2008
1Thalidomide (Thalomid)FDA Link
07/2008
1Dexamethasone (Maxidex)FDA LinkGeneric
07/2008
1AlkaloidsIBA
03/2006
1thiocoralineIBA
08/2003

Therapy/Procedure

2Therapeutics
01/2018 - 10/2016
1Drug Therapy (Chemotherapy)
05/2021